|
Saw Palmetto
The effect of Permixon on androgen receptors.
This study shows that Saw Palmetto extract was
able to effectively reduce Binding of Testosterone and DHT to their receptors on
various tissues.
Author: el-Sheikh MM; Dakkak MR;
Saddique A
Journal: Acta Obstet Gynecol
Scand, 67: 5, 1988, 397-9
Abstract: Permixon, the
liposterolic extract of the plant Serenoa Repens is a recently introduced drug
for the treatment of benign prostatic hyperplasia. The effect of Permixon on
dihydrotestosterone and testosterone binding by eleven different tissue
specimens was tested. The drug reduced the mean uptake of both hormones by 40.9%
and 41.9% respectively in all tissue specimens. Since hirsutism and virilism are
among other gynecological problems caused either by excessive androgen
stimulation or excess endorgan response, we suggest that Permixon could be a
useful treatment in such conditions and recommend further investigations of the
possible therapeutic values of the drug in gynecological practice.
|
